Robotic adventures in crystallisation space
نویسندگان
چکیده
منابع مشابه
Further adventures in shape space
It has been a long-held assumption in ligand-based virtual screening that the bioactive conformation of a molecule is privileged. The assumption is that superior performance in 3D searching (pharmacophores, shape similarity) should be obtained when using the bioactive conformation of a query molecule for searching for other active molecules. A parallel assumption has been that extensive samplin...
متن کاملAdventures in de Sitter space
This is my contribution to the Festschrift honoring Stephen Hawking on his 60th birthday. Twentyfive years ago, Gibbons and Hawking laid out the semi-classical properties of de Sitter space. After a summary of their main results, I discuss some further quantum aspects that have since been understood. The largest de Sitter black hole displays an intriguing pattern of instabilities, which can ren...
متن کاملAdventures in time and space
C of pre-mRNA splicing is a critical part of the eukaryotic gene expression process. Extensive evidence indicates that transcription and splicing are spatiotemporally coordinated and that most splicing events occur co-transcriptionally. A kinetic coupling model has been proposed in metazoans to describe how changing RNA Polymerase II (RNAPII) elongation rate can impact which alternative splice ...
متن کاملAdventures in the ( not so ) Complex Space ∗
We report on the progress of a constructive mechanization for a small subset of signal processing theory, built upon the SSREFLECT and MATHCOMP libraries. The development was started to provide mechanized semantics for audio programming languages. Currently, we have formalized several standard properties of the Discrete Fourier Transform, such as its unitary matrix form and its power and convol...
متن کاملStuck in a What? Adventures in Weight Space
Deep learning researchers commonly suggest that converged models are stuck in local minima. More recently, some researchers observed that under reasonable assumptions, the vast majority of critical points are saddle points, not true minima. Both descriptions suggest that weights converge around a point in weight space, be it a local optima or merely a critical point. However, it’s possible that...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2005
ISSN: 0108-7673
DOI: 10.1107/s0108767305085661